Synthesis and Characterization of Hydroxyapatite Nanoparticles using Wet Chemical Method

Authors: V. Kalaiselvi, R. Mathammal, P. Anitha,
Abstract: Calcium Phosphate is an attractive biomedical materials owing to their excellent biocompatibility and non- toxicity of their chemical components. It exists in different crystalline phases and different Ca/P ratios, such as Hydroxyapatite, Octacalcium phosphate and Tricalcium phosphate. Among the Calcium Phosphate, Hydroxyapatite Ca10 (PO4)6(OH)2 has been used to manufacture biomaterials of hard tissue repair and replacement. In the present work, hydroxyapatite was synthesized using wet chemical method. The synthesized samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). X- ray diffraction (XRD) analysis show that the synthesized samples appeared in single phase Hexagonal structure. The crystallite size increases from 10nm to 50nm with respect to increment of calcined temperature from 400 to 700C. FTIR spectra reveal the presence of characteristic phosphate, hydroxide and water bands of Hydroxyapatite in all the prepared samples. The SEM analysis shows the formation of nanorod morphology. Results from the above mentioned characterization predicts that increment of calcinations temperature enhanced the crystalline nature and crystalline size of the nanoparticles.