In the present study, the Au/Ag doped nano sized hydroxyapatite was synthesize from the combination of low cost dead Mussel shell (Mollusk) as calcium source with di-ammonium hydrogen phosphate (NH4)2HPO4 as a phosphate source, at the same time as maintain the pH at 10 using ammonium hydroxide (NH4OH), followed by microwave irradiation for 30 min. The deposit was collected and calcined at 900°C for 2h, after the decomposition of the organic residue and carbonate phases. Synthetically this procedure contains right of way than other events for the reason that it is more facile and suitable method concerning such a biological ravage material of remaining mussel-shell. The functional groups, structural, morphological studies and the elemental analysis of the entire yield were characterized by different systematic techniques.