Polycrystalline Zn-Ni-Cu ferrite with general formula Zn0.1Ni0.4Cu0.5Fe2O4 ferrite has been prepared by solid state method. In order to explore the structural parameters of prepared samples were characterized by using X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FT-IR) technique. The lattice parameter was found to 8.463A0. Texture coefficient (TC) of (422) is 2.1212.The orientation grain growth is more in (422) plain. The FT-IR spectra of spinel ferrite and has attributed the band around 600 cm-1 to the intrinsic vibrations of tetrahedral complexes corresponding to the highest restoring force and the band around 400 cm-1 to intrinsic vibrations of octahedral complexes. Crystallite size (D), interatomic bond-lengths, hopping lengths, train and dislocation density also reported.